Knee Research

Changes in Patellofemoral Motion After ACL Reconstruction

The purpose of this project is to evaluate the effects of ACL injury and reconstruction on patello-femoral motion, and determine whether the choice of ACL graft (BTB or hamstrings tendon) affects knee kinematics.
Principal Investigators: William Anderst, PhD and Bryson Lesniak, MD

Functional Biomechanical Outcome of ACL-reconstruction vs. ACL-reconstruction and extra-articular-tenodesis

The purpose of this study is to asses functional biomechanical outcomes and patient reported outcome measures following single bundle ACL reconstruction (ACL-R) compared to single bundle ACL reconstruction and extra articular tenodesis (ACL-R+EAT). While rotatory knee instability is multifactorial, well performed individualized anatomic ACL-R should be sufficient to restore native knee stability. Although extra-articular tenodesis combined with ACL-R has the potential to decrease rotatory instability, there is a high risk of lateral compartment over constraint, altered knee kinematics, and premature osteoarthritis. However, there is no functional biomechanical data that compares isolated ACL-R to ACL-R+EAT.

Principal Investigator: Volker Musahl, MD
Co-Investigators: Bryson Lesniak, MD and William Anderst, PhD

This study aims to provide new, novel information regarding in vivo, three-dimensional kinematics of the knee following arthroplasty utilizing the Navio system.

Principal Investigators: William Anderst, PhD and Ken Urish, MD
Co-Investigators: Brian Hamlin, MD

Bilateral Knee Kinematics in High and Low- Functioning Patients After Total Knee Arthoplasty

This study aims to identify differences in knee kinematics in high and low functioning patients after total knee arthroplasty.

Principal Investigators: Brian Klatt, MD
Co-Investigators: William Anderst, Ph.D. and Sara Piva PhD
Funding: Orthopaedic Research and Education Foundation

Knee Kinematics in Athletes

The overall goal of this project is to characterize knee kinematics in healthy young adult athletes during dynamic movements. We seek to quantify side-to-side symmetry in knee kinematics, arthrokinematics (i.e. cartilage contacts), and ACL elongation, which are often used to evaluate functional performance after injury and treatment (conservative or surgical). By determining the side-to-side symmetry in healthy knees, we will develop a reference standard that can be used to evaluate the efficacy of surgery or conservative treat

Principal Investigators: William Anderst, Ph.D
Co-Investigators: Freddie Fu, MD, Bryson Lesniak, MD, Volker Musahl, MD